Cleveland Heartlab

Microalbumin/Creatinine Ratio

CPT Code: 82043/82570

Order Code: C151, C919 (for ratio)

Synonyms: MACR

Sample Type: Random urine

Minimum Volume: 5.0 mL

Tube Type: Yellow-top urine specimen tube

Collection: Use a clean urine container to collect a random urine sample and transfer to a yellow-top urine specimen tube using the vacutainer system. The sample should be collected without preservatives.

Storage Instructions: Cleveland HeartLab recommends that samples be stored at 4°C and shipped same day as draw.  The sample is stable for up to 4 days at 4°C.

Causes of rejection: Samples will be rejected if the yellow-top urine specimen tube is cracked/leaking, or improperly labeled. Samples will also be rejected if the sample is grossly bloody.

Use: Evaluation of early diabetic renal disease

Methodology: Immunoturbidimetric Assay Tina-quant®

Goal Value: <30 mg/g

Additional Information: Samples should not be collected after exertion, in the presence of urinary tract infection, during acute illness, immediately after surgery, or after an acute fluid load. Specimens should be collected without preservatives.

Studies have shown that elevated levels of urinary albumin in people with diabetes or hypertension are associated with increased risk of developing cardiovascular disease (CVD), even if those levels are within the normal reference range. More recently, research has been focused on trying to determine if increased levels of albumin in the urine are also indicative of CVD risk in those who do not have diabetes or high blood pressure.
 
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