NMR LipoProfile®
CPT Code: 83704
Order Code: C907
Synonyms:
Sample Type: Serum, plasma
Minimum Volume: 1.0 ml
Tube Type: NMR LipoProfile® tube (black-top with yellow ring)
Collection:
1. Draw the sample and gently invert 5 times (DO NOT SHAKE!)
2. Let the blood clot for 30 minutes
3. Centrifuge sample at 1300 rcf for 30 minutes
Storage Instructions: Cleveland HeartLab recommends that the sample be stored at 4°C and shipped the same day as draw. The sample is stable for 10 days at 4°C.
Causes of Rejection: The sample will be rejected if there is gross hemolysis or if the sample is improperly labeled.
Use: The
NMR LipoProfile® can be used to directly measure LDL particle number (LDL-P) and identify insulin resistance/metabolic syndrome.
Methodology: Nuclear Magnetic Resonance (NMR) spectroscopy
Goal Value:
LDL-P: <1000 nmol/L
HDL-P: >30.5 umol/L
Total Cholesterol: <200 mg/dL
LDL-C: <100 mg/dL
HDL-C: ≥40 mg/dL
Triglycerides: <150 mg/dL
LP-IR Score: <45
Small LDL-P: <527 nmol/L
LDL Size: >20.8 nm
Large HDL-P: >4.8 umol/L
HDL Size: >9.2 nm
Large VLDL-P: <2.7 nmol/L
VLDL Size: <46.6 nm
Additional Information: LDL Particle Size (small), Large HDL (low levels), and Large VLDL (high levels) contribute to CHD risk and are important markers of the Metabolic Syndrome and risk of developing Type 2 Diabetes Mellitus.