DHEA-S

Cleveland HeartLab D, Test

NEW YORK DOH APPROVED: YES
CPT Code: 82627
Order Code: C385
ABN Requirement: No
Synonyms: Dehydroepiandrosterone Sulfate; DHEA-SO4; DHEA Sulfate
Specimen: Serum
Volume:  0.5 mL
Minimum Volume:  0.3 mL
Container: Gel-barrier tube (SST, Tiger Top)

Collection:

  1. Collect and label sample according to standard protocols.
  2. Gently invert tube 5 times immediately after draw. DO NOT SHAKE.
  3. Allow blood to clot 30 minutes.
  4. Centrifuge at 1300 rcf for 10 minutes.

Special Instructions: Samples should not be taken from patients receiving therapy with high biotin doses (>5 mg/day) until at least 8 hours following the last biotin administration.

Transport:   Store serum at 2°C to 8°C after collection and ship the same day per packaging instructions provided with the Cleveland HeartLab, Inc. shipping box.

Stability:

Ambient (15-25°C): 7 days
Refrigerated (2-8°C): 7 days
Frozen (-20°C): 2 months
Deep Frozen (-70°C): 2 months

Causes for Rejection: Specimens other than serum; improper labeling; samples not stored properly; samples older than stability limits

Methodology: Electrochemiluminescence Immunoassay (ECLIA)

Turn Around Time: 1 to 5 days

Reference Range:

Age Male, ug/DL Female, ug/DL
 <1 Week 108.0 – 607.0 108.0 – 607.0
 1 – 4 Weeks 31.6 – 431.0 31.6 – 431.0
 4 Weeks – 1 Year 3.4 – 124.0 3.4 – 124.0
 1 – 4 Years 0.5 – 19.4 0.5 – 19.4
 5 – 9 Years 2.8 – 85.2 2.8 – 85.2
 10 – 14 Years 24.4 – 247.0 33.9 – 280.0
 15 – 19 Years 70.2 – 492.0 65.1 – 368.0
 20 – 24 Years 211.0 – 492.0 148.0 – 407.0
 25 – 34 Years 160.0 – 449.0 98.8 – 340.0
 35 – 44 Years 88.9 – 427.0 60.9 – 337.0
45 – 54 Years 44.3 – 331.0 35.4 – 256.0
 55 – 64 Years 51.7 – 295.0 18.9 – 205.0
 65 – 74 Years 33.6 – 249.0 9.4 – 246.0
≥75 Years 16.2 – 123.0 12.0 – 154.0

 

Intended Use:  The DHEA-S test can be used to identify the presence and source of excessive androgen production, as well as for the diagnosis of congenital adrenal hyperplasia.