Lipoprotein (a)

Cleveland HeartLab L, Lipids, Test

CPT Code: 83695
Order Code: C124
ABN Requirement:  No
Synonyms: Lipoprotein Little a; Lp(a)
Specimen: Serum
Volume: 0.5 mL
Minimum Volume: 0.2 mL
Container: Gel-barrier tube (SST, Tiger Top)


  1. Collect and label sample according to standard protocols.
  2. Gently invert tube 5 times immediately after draw. DO NOT SHAKE.
  3. Allow blood to clot 30 minutes.
  4. Centrifuge at 1300 rcf for 10 minutes.

Transport: Store serum at 2°C to 8°C after collection and ship the same day per packaging instructions provided with the Cleveland HeartLab, Inc. shipping box.


Ambient (15-25°C): not acceptable
Refrigerated (2-8°C): 14 days
Frozen (-20°C): >14 days
Deep Frozen (-70°C): >14 days

Causes for Rejection: Specimens other than serum; improper labeling; samples not stored properly; samples older than stability limits

Methodology: Immunoturbidimetric

Turn Around Time: 1 to 3 days

Relative Risk:

Age Low Risk
Moderate Risk
High Risk
All Ages <30 na >29


Intended Use : A Lp(a) test can be used to assess cardiovascular disease risk and guide treatment of lipoprotein abnormalities in individuals with a family history of premature coronary heart disease, a genetic predisposition for hypercholesterolemia, established atherosclerosis and a normal routine lipid profile, hyperlipidemia refractory to treatment, or a history of recurrent arterial stenosis.

Limitations: Intake of alcohol, aspirin, niacin, and estrogen supplements have the potential of causing a misrepresentation of the true Lp(a) concentrations. This assay has not been tested for interference by statin therapy.