NMR LipoProfile®

Cleveland HeartLab Lipids, N, Test

CPT Code: 83704; 80061 (with lipid panel)
Order Code:

  • C907 (LipoProfile® with Lipid Panel)
  • C944 (LipoProfile® without Lipid Panel)

ABN Requirement:  No
Synonyms: NMR
Specimen: Serum
Volume: 2.0 mL (4.0 mL with Lipid Panel)
Minimum Volume: 1.0 mL (2.0 mL with Lipid Panel)
Container: Red Top (no gel barrier) tube preferred


  1. Collect and label sample according to standard protocols.
  2. Gently invert tube 5 – 10 times immediately after draw. DO NOT SHAKE.
  3. Allow blood to clot 30 minutes in an upright position at room temperature.
  4. Centrifuge for 10 minutes.
  5. Aliquot serum into a labeled transport tube and cap tightly.

Patient Preparation: Patient should be fasting 12 hours prior to collection.

Transport: Store serum at 2°C to 8°C after collection and ship the same day per packaging instructions provided with the Cleveland HeartLab shipping box.


Ambient (15-25°C): not acceptable
Refrigerated (2-8°C): 6 days
Frozen (-20°C): not acceptable
Deep Frozen (-70°C): not acceptable

Causes of Rejection: Gross hemolysis; improper labeling; samples not stored properly; samples older than stability limits

Methodology: Nuclear Magnetic Resonance (NMR) Spectroscopy

Performing Laboratory: 

LabCorp Burlington
1447 York Court,
Burlington NC 27215-3361

Turn Around Time: 5 days

Reference Ranges:

Test ComponentReference RangeGoalModerate RiskHigh Risk
LDL Particle Number N/A< 1000 nmol/L1000-1599 nmol/L> 1599 nmol/L
LDL Cholesterol, Calculated (>19 years)N/A< 100 mg/dL100-129 mg/dL> 129 mg/dL
HDL-CN/A≥ 40 mg/dLN/AN/A
Triglycerides (>19 years)0-149 mg/dL< 150 mg/dLN/A> 149 mg/dL
Cholesterol, Total (>19 years)100-199 mg/dL< 200 mg/dLN/AN/A
HDL-Particle NumberN/A≥ 30.5 umol/L26.7-30.4 umol/L< 26.7 umol/L
Small LDL-Particle NumberN/A≤ 527 nmol/L528-839 nmol/L> 839 nmol/L
LDL Size> 20.5 nmN/AN/AN/A
Large VLDL-PN/A≤ 2.7 nmol/L2.8-6.9 nmol/L> 6.9 nmol/L
Large HDL-PN/A≥ 4.8 umol/L3.1-4.7 umol/L< 3.1 umol/L
VLDL SizeN/A≤ 46.6 nm46.7-52.5 nm> 52.5 nm
HDL SizeN/A≥ 9.2 nm8.9-9.1 nm< 8.9 nm
LP-IR ScoreN/A≤ 4546-63> 63

Use: The NMR LipoProfile® test may be ordered for individuals with obesity, metabolic syndrome or diabetes, individuals who have had a myocardial infarction or who have a family history of cardiovascular disease and individuals with low HDL and high triglyceride levels.

Limitations: The LDL-C and LP-IR Scores will be inaccurate if the patient is not fasting.

Additional Information: LDL Particle Size (small), Large HDL (low levels), and Large VLDL (high levels) contribute to CHD risk and are important markers of the Metabolic Syndrome and risk of developing Type 2 Diabetes Mellitus.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.