Epstein-Barr Virus Antibody to Early Antigens
CPT Code: 86663
Order Code: C1390
ABN Requirement: No
Synonyms: EBV EA Antibody; Epstein-Barr Virus Early Antigen Antibody IgG
Volume: 1.0 mL
Minimum Volume: 0.5 mL
Container: Gel-barrier tube (SST, Tiger Top)
- Collect and label sample according to standard protocols.
- Gently invert tube 5 times immediately after draw. DO NOT SHAKE.
- Let tube stand in a vertical position to allow blood to clot 30 minutes.
- Centrifuge for 10 minutes.
Transport: Store serum at 2-8°C after collection and ship the same day per packaging instructions provided with the Cleveland HeartLab shipping box.
Ambient (15-25°C): 4 days
Refrigerated (2-8°C): 7 days
Frozen (-20°C): 30 days
Deep Frozen (-70°C): 30 days
Causes for Rejection: Specimens other than serum; improper labeling; samples not stored properly; samples older than stability limits; grossly hemolyzed or grossly lipemic specimens; icteric specimens; microbially contaminated specimens
Methodology: Immunoassay (IA)
Turn Around Time: 4-5 days
|All Ages||Negative: ≤0.90|
|All Ages||Equivocal: 0.91-1.09|
|All Ages||Positive: ≥1.10|
Clinical Significance: Primary infection by Epstein-Barr Virus (EBV) causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders, including tumors. IgG recognizing early antigen D typically appears within a month after clinical presentation and is transient, lasting only 3-4 months. Persistently elevated levels suggest reactivation or persistence of EBV infection.
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