Choline, TMAO and Heart Health

Cleveland HeartLab TMAO

Powerful new evidence from the Cleveland Clinic confirms a link between choline, a nutrient naturally found in foods like red meat, egg yolks and dairy products, and the risk of dangerous blood clotting. Choline interacts with gut bacteria to make the blood more prone to clotting by helping to produce a compound called, trimethylene N-oxide (TMAO). Elevated blood levels of more »

The Gut, the Heart, and TMAO

Cleveland HeartLab heart attack and stroke, TMAO

The Surprising Link Between the Gut and Heart Health Science has long recognized that what we eat plays a critical role in our heart health. Now the details of this complex connection are coming into focus. One of the more intriguing recent discoveries has to do with the role of the gut microbiome—the trillions of microbes that reside in the more »

Could Food Be a New Medicine to Fight Heart Disease?

Cleveland HeartLab diet, heart attack and stroke, metabolic syndrome

A compound called DMB (3,3-dimethyl-1-butanol), found in olive oil, red wine and other foods, may someday be a first-of-its kind drug with the potential to treat—or even prevent—heart disease in the future, suggests a new Cleveland Clinic study published in the journal Cell. The investigators report that in mice, dietary supplementation with this naturally occurring compound safely inhibited atherosclerosis (plaque more »

3 New Tests to Predict Heart Attack and Stroke Risk

Cleveland HeartLab biomarkers, inflammation, metabolic syndrome, TMAO

Three new blood tests can help identify hidden risk for a heart attack or stroke in seemingly healthy patients—before symptoms strike. The new tests, now available through Cleveland HeartLab (CHL), check levels of certain biomarkers that have been linked to cardiovascular danger in peer-reviewed studies. Cardiovascular disease (CVD) is the leading killer of men and women, accounting for one in more »

TMAO Testing: A New Way To Assess Heart Attack And Stroke Risk

Cleveland HeartLab biomarkers, heart attack and stroke, TMAO

A new blood test that measures levels of TMAO (trimethylamine-N-oxide) — a metabolite derived from gut bacteria — can powerfully predict future risk for heart attack, stroke, and death in patients who appear otherwise healthy, according to pioneering Cleveland Clinic research. The new test — now available through Cleveland HeartLab — measures blood levels of TMAO, a compound produced by more »