Apolipoprotein A1 (ApoA1)

Cleveland HeartLab A, Lipids, Test

NEW YORK DOH APPROVED: YES
CPT Code: 82172
Order Code: C122
ABN Requirement:  No
Synonyms: A-1 Apolipoprotein; Apo A-1, Apo A
Specimen: Serum
Volume: 1.0 mL
Minimum Volume: 0.5 mL
Container: Gel-barrier tube (SST, Tiger Top)

Collection:

Serum:

  1. Collect and label sample according to standard protocols.
  2. Gently invert tube 5 times immediately after draw. DO NOT SHAKE.
  3. Allow blood to clot 30 minutes.
  4. Centrifuge for 10 minutes.

Patient Preparation: Patient should be fasting 12 to 14 hours.

Transport: Store serum at 2°C to 8°C after collection and ship the same day per packaging instructions included with the provided shipping box.

Stability:

Ambient (15-25°C): 7 days
Refrigerated (2-8°C): 10 days
Frozen (-20°C): 30 days

Causes for Rejection: Specimens other than serum; improper labeling; samples not stored properly; samples older than stability limits; gross hemolysis; gross icterus; gross lipemia

Methodology: Immunoturbidimetric Assay

Turn Around Time: 1 to 3 days

Relative Risk:

AgeSex
Low Risk
mg/dL
Moderate Risk
mg/dL
High Risk
mg/dL
<20 YearsMale, Female>120115-120<115
≥20 YearsMale≥115N/A<115
≥20 YearsFemale≥125N/A<125

Clinical Significance: Apolipoprotein A1 is the primary protein associated with HDL cholesterol. Like HDL cholesterol, increased concentrations are associated with reduced risk of cardiovascular disease.

Limitations: In very rare cases gammopathy, particularly of the monoclonal IgM type (e.g., Waldenstrom macroglobulinemia), may cause unreliable results.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.