Cleveland HeartLab C, Test

CPT Code: 82390
Order Code: C1369
ABN Requirement: No
Synonyms: Wilson’s Disease; Copper Oxide
Specimen: Serum
Volume:  1.0 mL
Minimum Volume:  0.5 mL
Container: Gel-barrier tube (SST, Tiger Top)



  1. Collect and label sample according to standard protocols.
  2. Gently invert tube 5 times immediately after draw. DO NOT SHAKE.
  3. Let tube stand in a vertical position to allow blood to clot 30 minutes.
  4. Centrifuge at 1300 rcf for 10 minutes at room temperature.

Transport: Store serum at 2-8°C after collection and ship the same day per packaging instructions provided with the Cleveland HeartLab, Inc. shipping box.


Ambient (15-25°C): 7 days
Refrigerated (2-8°C):
60 days
Frozen (-20°C):
90 days
Deep Frozen (-70°C):
90 days

Causes for Rejection: Specimens other than serum; improper labeling; samples not stored properly; samples older than stability limits

Methodology: Nephelometry (NEPH)

Turn Around Time: 4 days

Reference Range:

Age Male, mg/dL Female, mg/dL
0-30 days 8-25 3-28
31 days-11 months 15-48 15-43
1-3 years 25-56 29-54
4-6 years 29-56 26-54
7-9 years 25-52 23-48
10-12 years 21-51 21-48
13-15 years 20-50 21-46
16-18 years 20-45 22-50
>18 years 18-36 18-53

Intended Use: Evaluation of Wilson’s disease (hepatolenticular degeneration), liver cirrhosis, and copper deficiency.

Limitations: Oral contraceptives may cause increased values. Because ceruloplasmin is an acute phase reactant, use caution in interpreting results where inflammation or infection are present.

Clinical Significance: Ordered with a blood or urine copper test, ceruloplasmin helps in the diagnosis of Wilson’s disease.