Cleveland HeartLab D, Test

CPT Code: 80162
Order Code: C2351
ABN Requirement: No
Synonyms: Lanoxin
: Serum
Volume:  1.0 mL
Minimum Volume:  0.3 mL
Container:Red Top (no gel barrier) tube


  1. Collect and label sample according to standard protocols.
  2. Gently invert tube 5 times immediately after draw. DO NOT SHAKE.
  3. Allow blood to clot 30 minutes.
  4. Centrifuge for 10 minutes.
  5. Aliquot serum into labeled transport tube and cap tightly.
  6. Store transport tube frozen at -20°C until ready to ship.

Special Instructions: Sample should be drawn between 5 and 7 hours after the last dose of digoxin. Record the time of the last dose of digoxin on the requisition.

Transport/Shipping Instruction: Store aliquoted serum at -20°C after collection and ship the same day per packaging instructions provided with the Cleveland HeartLab shipping box.

  • Please note:ship frozen aliquoted serum on dry ice.


Ambient (15-25°C): Not Acceptable
Refrigerated (2-8°C): 24 hours
Frozen (-20°C): 1-2 weeks
Deep Frozen (-70°C): 1-2 weeks

Causes for Rejection: Specimens other than serum; improper labeling; samples not stored properly; samples older than stability limits

Methodology: Kinetic Interaction of Microparticles in a Solution

Turn Around Time: 2-3 days

Reference Range:

Age ng/mL
All Ages 0.6-1.2

Urgent Values:

Age ng/mL
All Ages >3.0

Use: Testing for digoxin is performed to evaluate and monitor drug levels in individuals receiving digoxin therapy, or individuals with a cardiac diagnosis for whom no accurate history on digoxin usage exists.

Limitations: Therapy with cardiac glycosides, such as digitoxin, may cause unreliable results. Falsely elevated results may occur if sample is not drawn at the specified time post administration of the drug.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.