Lipid Panel

Cleveland HeartLab L, Lipids, Test

CPT Code: 80061; (and 83721 if Direct LDL performed)

Order Code:
Lipid Panel: C906 (includes Total Cholesterol, Triglyceride, Direct HDL, Calculated LDL and Non-HDL Cholesterol)
Lipid Panel and Direct LDL Cholesterol Reflex: C909 (includes Total Cholesterol, Triglyceride, Direct HDL, and Non-HDL Cholesterol.  If Triglycerides are greater than 400 mg/dL, then LDL Cholesterol, Direct will be performed at an additional charge (CPT 83721).)

Refer to individual tests for assay information.
ABN Requirement:  No
Specimen: Serum
Volume: 2.0 mL
Minimum Volume: 1.0 mL
Container: Gel-barrier tube (SST, Tiger Top)


  1. Collect and label sample according to standard protocols.
  2. Gently invert tube 5 times immediately after draw. DO NOT SHAKE.
  3. Allow blood to clot 30 minutes.
  4. Centrifuge for 10 minutes.

Patient Preparation: Fasting is preferred

Transport: Store serum at 2° to 8°C after collection and ship the same day per packaging instructions provided with the Cleveland HeartLab shipping box.


Ambient (15-25°C): not acceptable
Refrigerated (2-8°C): 7 days
Frozen (-20°C): 14 days
Deep Frozen (-70°): 30 days 

Causes of Rejection: Specimens other than serum; improper labeling; samples not stored properly; samples older than stability limits.

Methodology: Photometric

Turn Around Time: 1 to 3 days

Relative Risk:

TestAgeLow Risk
Moderate Risk
High Risk
Cholesterol0-19 years<170170-199>199
20-24 years<190190-224>224
≥25 years<200200-239>239
Triglyceride0-9 years<7575-99>99
10-19 years<9090-129>129
20-24 years<115115-149>149
≥25 years<150150-199>199
HDL, Direct0-19 years>45N/A<50
≥20 years, Female>49N/A<50
≥20 years, Male>39N/A<40
LDL, Calculated0-19 years<110110-129>129
20-24 years<120120-159>159
≥25 years<100100-129>129
Non-HDL Cholesterol0-19 years<120120-144>144
20-24 years<150150-189>189
≥25 years<130130-159>159
LDL, Direct0-19 years<110110-129>129
20-24 years<120120-159>159
≥25 years<100100-129>129

Use: The lipid panel is used, along with other tests, during routine assessment to determine an individual’s risk of cardiovascular disease. A lipid panel can also be used to monitor the efficacy of lifestyle interventions or medications.

Limitations: Intralipid causes artificially high LDL cholesterol results. In some patients with abnormal liver function, the LDL-cholesterol result is significantly negatively biased versus beta quantification results. In very rare cases gammopathy may cause unreliable results.

Additional Information: Adults without other risk factors for heart disease should receive a lipid panel once every five years. Individuals who have had an abnormal lipid panel, or those who have other cardiovascular risk factors, may be tested more frequently.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.