Mercury, Blood

Cleveland HeartLab M, Test

CPT Code: 83825
Order Code: C2395
ABN Requirement: No
Specimen: Whole Blood
Volume:  7.0 mL
Minimum Volume:  0.5 mL
Container: EDTA (Navy Blue top) tube


  1. Draw and gently invert 8 to 10 times.
  2. Label tube with patient information.
  3. Store collection tube refrigerated at 2-8°C until ready to ship.

Transport: Store navy blue EDTA whole blood at 2-8°C after collection and ship the same day per packaging instructions provided with the Cleveland HeartLab shipping box.

Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patient should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications, and avoid shellfish and seafood for 48-72 hours.


Ambient (15-25°C): 7 days
Refrigerated (2-8°C):
7 days
Frozen (-20°C):
Not Acceptable

Stability Note: Mercury is volatile; concentration may reduce after 7 days of storage at ambient and/or refrigerated temperatures.

Causes for Rejection: Specimens other than EDTA (Navy Blue top) whole blood; improper labeling; samples not stored properly; samples older than stability limits

Methodology: Atomic Absorption (AAB), Inductively Coupled Plasma/Mass Spectrometry (ICP-MS)

Turn Around Time: 5-7 days

Reference Range:

Age ug/L
All Ages 0.0-10.0

Intended Use: The mercury test is used for the determination of total mercury levels.

Clinical Significance: Preferred test for the assessment of acute mercury exposure. Blood mercury levels predominantly reflect recent exposures, and they are most useful in the diagnosis of acute poisoning as blood mercury concentrations rise sharply and fall rapidly over several days after ingestion. Blood concentrations in unexposed individuals rarely exceed 20 ug/L. The reference interval relates to inorganic mercury concentrations. Dietary and non-occupational exposure to organic mercury forms may contribute to an elevated total mercury result. Clinical presentation after toxic exposure to organic mercury may include dysarthria, ataxia and constricted vision fields with mercury blood concentrations from 20 to 50 ug/L. Elevated results may be due to skin or collection-related contamination, including the use of a non-certified metal-free collection/transport tube. If contamination concerns exist due to elevated levels of blood mercury, confirmation with a second specimen collected in a certified metal-free tube is recommended. Mercury is volatile; concentration may decrease over time.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.