sd-LDL

Cleveland HeartLab Lipids, S, Test

NEW YORK DOH APPROVED: YES

CPT Code: 83722
Order Code: 1341
ABN Requirement:  No
Synonyms: Small Dense LDL; Small Dense Low-density Lipoprotein; sdLDL
Specimen: Serum
Volume: 0.5 mL
Minimum Volume: 0.2 mL
Container: Gel-barrier tube (SST)

Collection:

  1. Collect and label sample according to standard protocols.
  2. Gently invert tube 5 times immediately after draw. DO NOT SHAKE.
  3. Allow blood to clot 30 minutes.
  4. Centrifuge for 10 minutes.

Special Instructions: At least 3 ml of blood should be drawn.

Patient Preparation: Fasting may be required for this test. Please ask your doctor if you should fast prior to testing.

Transport: Store serum at 2°C to 8°C after collection and ship the same day per packaging instructions included with the provided shipping box.

Stability:

Ambient (15-25°C): not acceptable
Refrigerated (2-8°C): 5 days
Frozen (-20°C): not acceptable
Deep Frozen (-70°C): >5 days

Causes for Rejection: Specimens other than serum; improper labeling; samples not stored properly; samples older than stability limits

Methodology: Immunoturbidimetric

Turn Around Time: 3 days

Relative risk:

Age Goal
mg/dL
Adults < 50.0

Clinical Significance: Individuals with sdLDL cholesterol levels ≥50.0 mg/dL had approximately 1.6-fold higher risk for incident CHD compared to those with <50 mg/dL over a 16-year follow-up period1.

Population reference interval for males 21-44 yrs and females 21-54 yrs is 12.7-48.3 mg/dL and for males 45-75 yrs and females 55-75 yrs is 12.6-51.7 mg/dL.

References:

  1. Hoogeveen RC, Gaubatz JW, Sun W, et al. Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. Arterioscler Thomb Vasc Biol. 2014 May;34(5):1069-77.

Limitations: Drawing less than 3 ml of blood in a serum separator tube (SST) may cause erroneous results.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.