CPT Code: 86300
Order Code: 5819
ABN Requirement: No
Synonyms: CA 15-3; Breast Cancer Antibody
Container: Gel-barrier tube (SST, Tiger Top)
Volume: 1.0 mL
-Note: 2.0 mL recommended for re-baselining
Minimum Volume: 0.5 mL
-Note: 1.0 mL recommended for re-baselining
- Collect and label sample according to standard protocols.
- Gently invert tube 10 times immediately after draw. Do not shake.
- Allow blood to clot 30 minutes.
- Centrifuge for 10 minutes.
Special Information: Results obtained with different methods or kits cannot be used interchangeably. Patients taking a biotin dose of up to 5 mg/day should refrain from taking biotin for 4 hours prior to sample collection. Patients taking a biotin dose of 5 to 10 mg/day should refrain from taking biotin for 8 hours prior to sample collection. Patients taking a biotin dose > 10 mg/day should consult with their physician or the laboratory prior to having a sample taken. Clinicians should consider biotin interference as a source of error, when clinically suspicious of the laboratory result.
Transport: Store serum at 2°C to 8°C after collection and ship the same day per packaging instructions included with the provided shipping box.
Ambient (15-25°C): 7 days
Refrigerated (2-8°C): 7 days
Frozen (-20°C): 28 days
Causes for rejection: Specimens other than serum; improper labeling; samples not stored properly; samples older than stability limits; gross hemolysis; gross lipemia
Methodology: Immunoassay (Siemens method: Quest Diagnostics, Roche method: Cleveland Clinic)
Turn Around Time: 2 to 3 days
Reference Range: See Laboratory Report
Clinical Significance: CA 15-3 may be useful for monitoring patients with metastatic breast cancer and certain ovarian cancers. The CA 15-3 values from sequential samples have a high correlation with the clinical course in most patients with metastatic breast cancer.
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.