Creatine Kinase

Cleveland Heartlab C, Standard Laboratory Tests, Test

CPT Code: 82550
Order Code: C137
ABN Requirement:  No
Synonyms: CK; Total CK; Creatine Phosphokinase; CPK
Specimen: Serum
Volume: 0.5 mL
Minimum Volume: 0.2mL
Container: Gel-barrier tube (SST, Tiger Top)


  1. Collect and label sample according to standard protocols.
  2. Gently invert tube 5 times immediately after draw. DO NOT SHAKE.
  3. Allow blood to clot 30 minutes.
  4. Centrifuge for 10 minutes.

Transport: Store serum at 2°C to 8°C after collection and ship the same day per packaging instructions included with the provided shipping box.


Ambient (15-25°C): 2 days
Refrigerated (2-8°C): 7 days
Frozen (-20°C): 4 weeks

Causes for Rejection: Specimens other than serum; improper labeling; samples not stored properly; samples older than stability limits; hemolyzed specimens

Methodology: Photometric

Turn Around Time: 1 to 3 days

Reference Range:

Age Male
All Ages 20-200 20-180

Priority Values:

AgePriority 2 Values (U/L)

≤18 years≥1000
>18 years≥6000

Clinical Significance: Creatine kinase testing may be ordered for individuals suspected of having a myocardial infarction or for evaluation of skeletal muscle damage. Elevated results may be due to: Myocarditis, Myocardial Infarction (heart attack), Muscular Dystrophy, Muscle Trauma or excessive exercise.

Limitations: Cyanokit (Hydroxocobalamin) may cause interference with results. In very rare cases gammopathy may cause unreliable results. Non-hemolyzed samples are recommended by the IFCC for testing. Highly lipemic specimens may cause unreliable results.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.